Tuesday, February 12, 2013

Milk thistle

Milk thistle, a flowering plant, has been known for nearly two millennia as a herb of therapeutic value. An extract from the fruit of the milk thistle (Silybum marianum) has been know for protecting the liver from damage by chemicals, alcohol, and other toxins. The liver-protecting functions are due to two main actions of Milk thistle: antioxidant and protein-restoring activities. The active constituent of Milk thistle is Silymarin- a flavonoid, also an antioxidant that fights against oxidative stress and thus inhibits inflammation of liver cells. It prevents toxic and foreign substances from penetrating liver cells by stabilizing the outer membrane of liver cells. Silymarin displaces toxins by binding to proteins and receptors on the cell membrane. Silymarin also has the ability to repair and restore the liver as it stimulates protein synthesis due to which new liver cells are able to grow. 

Effective for:
  • Cholestasis of pregnancy 
  • Cirrhosis 
  • Fatty liver 
  • Gall stones 
  • Helps with diabetes by lowering insulin resistance 
  • Helps with eczema and psoriasis 
  • Improve digestion and liver function 
  • Lowers LDL 

Supplements:
Milk thistle is prepared as a concentrated extract of standardized dried herb (70% to 80%, or approximately 140 mg silymarin). Silymarin must be concentrated because it is poorly absorbed from the gastrointestinal tract. 

Recommended Dose:
  • 200 to 400 mg silymarin per day 

Side effects and precautions:

  • Milk thistle extracts appear to be safe and generally well-tolerated with negligible, if any, toxicity or adverse side effects. 
  • Milk thistle occasionally has a mild laxative effect due to increased bile flow and secretion. 
  • Allergic reactions are a concern as anyone with allergies to asters, daisies, artichokes, thistle or kiwi should avoid milk thistle and its constituents.

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